Placed profiled RGB will allow you to make CMYK conversions to the required destination on export-you could also leave the profiled RGB color unchanged in the PDF and let the conversion happen when the magazine is output. If a work flow requires output to different print destinations, you should be placing profiled RGB images and not making CMYK conversions in Photoshop. If you asked me, I'd go for it and not look back.
But as a practical matter, you're doing it at the deep end of what you can - and cannot - reproduce in print. By definition, that is cause for some concern. In technical terms, you are actually altering the job. And if you're sverely concerned, run proofs of both of them to see if you can find any differences. As far as "Convert to destination" modifications, you can test it yourself by creating separate, differently named PDF files with and without conversion. If your print provider gave it to you, for output on their systems, the place to start would be to ask them about the issue, and whether it would be relevant to them. You install them and use them they're not the kind of thing where mere mortals can poke under the hood and make minor changes without risking severe consequence. ICC profiles are effectively a black box.
The first question would be: Where did the ICC profile come from? Quickly followed with: Who made it?
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